What is Xanax used for?

XANAX

What is Xanax used for? formally know as alprazolam, is a short-acting benzodiazepine, that is used to treat anxiety disorders including panic disorder. It is also used to help wean individuals from alcohol dependence in order to avoid alcohol withdrawal, which can lead to seizures. Benzodiazepines are also known for their strong addiction potential and have resulted in approximately 8,000 overdose deaths in 2015 in the United States. Their withdrawals alone can result in seizures and even death and therefore individuals taking benzodiazepines usually need to be slowly weaned in order to prevent deadly withdrawals.  Benzodiazepines work on the same receptors in the brain as alcohol. These are known as gamma-aminobutyric acid (GABA) receptors. Enhanced GABA activity results in sedation, muscle relaxation, anxiolytic effects and anticonvulsant effects and therefore this class of medication is necessary to treat certain disorder however it has a very strong addiction potential and when abused can cause severe damage. Additionally when benzodiazepines are co-ingested with alcohol, side effects can be potentiated. Although overdose is known to occur, withdrawing from benzodiazepines, like alcohol, can be deadly and often a slow taper of benzodiazepines is necessary to prevent withdrawal seizures.

What is Xanax used for? as a street drug

Xanax was the most commonly prescribed prescription psychiatric medication from 2005 to 2013 in the United States and although it has allowed many individuals to regain control of their anxiety and their life, it also became a widely used and abused addictive drug. Xanax works within minutes of entering the bloodstream and peaks within hours and results in a state of pleasure and euphoria and as a result, many individuals use this drug for recreational purposes rather than medical purposes. Due to the recreational popularity of this drug, Xanax is a well-known street drug that is often used to enhance the effects of alcohol in social situations such as parties and concerts. Xanax abuse can elicit pleasurable effects such as lightheadedness, a sense of unreality, a feeling of detachment, an emotional numbness and a greater sexual inclination.

Facts about Xanax

  • 55 percent of nonmedical users acquired prescription painkillers (including Xanax) for free from a friend or relative
  • 3 percent abused medications that were prescribed by their own doctor
  • 4 percent bought them from a friend or relative
  • 8 percent sneaked from a friend or relative
  • Whereas only 4.4 percent bought them from a dealer.
  • Seventy percent of teenagers battling a Xanax addiction acquired the drug from their family’s medicine cabinet.
  • Emergency room visits owing to recreational abuse of Xanax escalated from 57,419 in 2005 to 124,902 in 2010.
  • In 2013, 50 million prescriptions were written for Xanax, an increase from 38 million prescriptions in 2006.
  • Prescription rates for Xanax have been at a steady increase of a 9 percent rate since 2008.

Withdrawal effects from Xanax

Although overdose can occur from Xanax, withdrawal from this medication can be deadly and therefore it is important to consult a medical professional if you are trying to wean yourself benzodiazepines. Like alcohol, the immediate cessation from benzodiazepines can result in seizures and therefore a slow taper must be initiated.  Common withdrawal effects include increased heart rate and blood pressure, agitation, and seizures.

Treatment for Xanax addiction

Xanax addiction, like alcohol, is usually treated with a slow taper of benzodiazepines to prevent seizures. Fumazenil (Romazicon) is a specific antidote for benzodiazepine toxicity however when used in acute overdose its potential risks may outweigh the benefits and therefore this medication remains controversial. Depending on the severity of the addiction and if there are co-occurring mental health conditions present, the duration and level of care may vary from inpatient hospitalization to outpatient therapy. Psychotherapy is needed in order to address the underlying behaviors leading to the addiction and to teach individual’s self-care and how to control their triggers and cravings.

Psychedelics online

Psychedelics online LSD Proven Safe in Landmark Trial

Psychedelics online despite its vast potential, LSD has been mostly off-limits to scientists for half a century, declared highly dangerous, even in small doses.

But Psychedelics online landmark placebo-controlled clinical trial found micro doses of LSD are physically safe, easing the drug’s path forward as a medicine.

Researchers in London with Eleusis, a private life-sciences company, asked 48 healthy, older adults without significant health problems to take 5, 10, or 20 micrograms every four days for three weeks — basically the Fadiman Protocol.

Psychedelics online other studies have looked at micro dosing’s affect on mood and cognition, with inconclusive results. This Phase 1 Psychedelics online study, in contrast, monitored all aspects of micro dozers’ health, from blood pressure to heart rates and rhythms to walking, talking, memory, and perception.

Micro dozers, researchers found, had no more negative side effects than a placebo. Cognition, balance, and coordination were not impaired — although micro dozers reported more headaches.

“The study provides reassuring safety data,” said Robin Carhart-Harris, head of the Centre for Psychedelic Research at Imperial College London, “and opens the door for larger scale clinical trials to evaluate the potential therapeutic effects of LSD.”

Eleusis plans to carry out Phase 2 studies for LSD for Alzheimer’s and other degenerative diseases.

Studies of micro dosing signal an expansion of the possibilities for psychedelics in the West, which burst into the scene in the 50s and 60s as a mind-expanding, culture-shaking bombshell, favored by monks and mystics plumbing the nature of mind and soul.

Psychonauts still seek God and Nature through psychedelics. But researchers also envision a whole new class of drugs aimed at dozens of psychological ailments. Psilocybin — a hallucinogen similar to LSD — has twice been declared a “breakthrough treatment” for depression when combined with therapy.

Less noticed has been psychedelics’ effects not on the mind and spirit, but the body. Long-distance runners and rock climbers report that LSD and mushrooms improve focus and lessen pain and fatigue.

So researchers are increasingly investigating the drugs’ effects on muscles and neurons. Focused on physical effects, Eleusis habitually calls them “serotonin 5-HT2A receptor agonists” — rather than psychedelics, hallucinogens, or entheogens.

Eleusis studies have found psychedelic-type drugs reduce inflammation in both mice with asthma and mice with a heart problem called coronary artery disease, which could lead to promising treatments of some of the most common health problems.

Serotonin receptors, which help regulate memory and cognition, degenerate in folks with Alzheimer’s, leading to some of the disease’s early signs, including depression and anxiety.

“Our research with serotonin 5-HT2A receptor agonists, such as LSD, suggest that they may represent a new strategy to treat diseases associated with chronic inflammation,” said Charles Nichols, co-author of the study and Professor of Pharmacology at Louisiana State University.

Eleusis’s studies hint at the intriguing possibility that healthy adults could take LSD the way they take Advil or aspirin — as a routine anti-inflammatory.

Micro dosing participants didn’t trip — didn’t feel “oceanic boundlessness,” synesthesia, or auditory hallucinations. They functioned normally.

But they did see the world differently in one fascinating way.

When shown a blue circle for a few seconds, then asked to guess how long the shape was visible, micro dozers overestimated the duration. The outside world, in other words, seemed to move more slowly.

Large doses of psychedelics famously dilate time; sunsets can seem to last for days. This study suggests micro dozers subjectively experience a few more moments in their day than the rest of us — even though they aren’t aware of it. (Results of this part of the study were published last year.)

Thanks to this study, time dilation —- and other effects of micro dosing — can now be studied more easily, and in more depth, clearing a path for clarity on whether micro dosing can be a helpful medicine for brain diseases, or add a few more microseconds to your day, possibly helping you find your flow.

“This groundbreaking Phase 1 trial,” said Shlomi Raz, Chairman and Founder of Eleusis, could help “unlock the therapeutic potential of psychedelics at subperceptual, non-psychoactive doses, to safely address the most urgent unmet needs in public health.”

Grow mushrooms

HOW TO GROW YOUR OWN MUSHROOMS

Grow mushrooms when it comes to ensuring the quality and safety of your mushrooms, DIY not only saves you money but eases the stress of securing a legitimate source. Not to mention, supporting to grow mushrooms on every step of their journey allows you to connect deeper with nature while creating self-reliance through maintaining growing mushroom reservoir of your choice. We understand growing your own mushrooms may sound a little intimidating which is why we’ve put together an easy “how-to” on how to build your own personal fungi kingdom, right from your apartment.

Need a quick rundown of psilocybin? Head to our Psilocybin Mushrooms Ultimate Guide.

Supplies

Grow mushrooms you’ll need a few materials to get started but don’t worry, this set up only needs to be purchased one-time, and is significantly more economical in the long run than purchasing a grow kit or buying by the gram.

Ingredients to Grow mushrooms

  • Spore syringe, 10-12 cc
  • Organic brown rice flour
  • Vermiculite, medium/fine
  • Drinking water

Equipment

  • 12 Shoulderless half-pint jars with lids (e.g. Ball or Kerr jelly or canning jars)
  • Hammer and small nail
  • Measuring cup
  • Mixing bowl
  • Strainer
  • Heavy-duty tin foil
  • Large cooking pot with a tight lid, for steaming
  • Small towel (or approx. 10 paper towels)
  • Micropore tape
  • Clear plastic storage box, 50-115L
  • Drill with ¼-inch drill bit
  • Perlite
  • Mist spray bottle

Hygiene Supplies Grow mushrooms

  • Rubbing alcohol
  • Butane/propane torch lighter
  • Surface disinfectant
  • Air sanitizer

To learn more about which spore variety you should choose, check out our grow guide.

PF Tek Method Grow mushrooms

This method of mushroom cultivation is cheap and pretty straightforward, therefore, perfect for the newbie fungi farmer and experienced “fungiculturist” alike.  For this process, you’ll prepare your substrate of brown rice flour, vermiculite, and water, and divide it between sterile glass jars. This allows you to control humidity while introducing air to the substrate providing the perfect environment for the mycelium to grow. After you’ve prepared the jars and divided the substrate, you’ll then introduce the spores and wait for the mycelium to develop. After about 4-5 weeks, transfer your colonized substrates, or “cakes”, to a fruiting chamber where you’ll wait for your mushrooms to grow. Check out the full step by step process of the PK Tek Method including preparation, inoculation, and colonization.

Preparing the Grow Chamber

So at this point, you’ve discarded any contaminated materials and consolidated the jars of your successful mycelium. Now it’s time to prepare your fruiting chamber and begin the birth process of your “cakes” or colonized substrates.

Make a shotgun fruiting chamber

  • Take your plastic storage container and drill ¼-inch holes roughly two inches apart all over the sides, base, and lid. To avoid cracking, drill your holes from the inside out into a block of wood.
  • Set the box over four stable objects, arranged at the corners to allow air to flow underneath. You may also want to cover the surface under the box to protect it from moisture leakage.

Add perlite

  • Place your perlite into a strainer and run it under the cold tap to soak.
  • Allow it to drain until there are no drips left, then spread it over the base of your grow chamber.
  • Repeat for a layer of perlite roughly 4-5 inches deep.

Fruiting

    • Open your jars and remove the dry vermiculite layer from each, taking care not to damage your substrates, or “cakes”, in the process.
    • Upend each jar and tap down onto a disinfected surface to release the cakes intact.
  • Rinse the cakes one at a time under a cold tap to remove any loose vermiculite, again taking care not to damage them.
  • Fill your cooking pot, or another large container, with tepid water, and place your cakes inside. Submerge them just beneath the surface with another pot or similar heavy item.
  • Leave the pot at room temperature for up to 24 hours for the cakes to rehydrate.
  • Remove the cakes from the water and place them on a disinfected surface.
  • Fill your mixing bowl with dry vermiculite.
  • Roll your cakes one by one to fully coat them in vermiculite. This will help to keep in the moisture.

Transfer to grow chamber

  • Cut a tin foil square for each of your cakes, large enough for them to sit on without touching the perlite.
  • Space these evenly inside the grow chamber.
  • Place your cakes on top and gently mist the chamber with the spray bottle.
  • Fan with the lid before closing.

Optimize and monitor conditions

  • Mist the chamber around four times a day to keep the humidity up, taking care not to soak your cakes with water.
  • Fan with the lid up to six times a day, especially after misting, to increase airflow.

Harvesting

The hard work is over. You’re now ready to sit back, relax, and watch for fruits (while still optimizing and monitoring conditions, of course). Your mushrooms, or fruits, will appear as tiny white bumps before sprouting into “pins.” After 5-12 days, they’ll be ready to harvest. When ready, cut your mushrooms close to the cake to remove. Don’t wait for them to reach the end of their growth, as they’ll begin to lose potency as they mature. It may not sound like a walk in the park, but the money you’ll save, the peace of mind you’ll gain, and the experience you’ll have under your belt will prove well worth it. The best news is, you’ll be able to re-use the same cakes up to three times!

Now, all there is to do is enjoy the fruits of your labor and with the long-term benefits of psilocybin, micro dosing is a facile way to implement psilocybin into your routine. Many who have integrated micro dosing psilocybin mushrooms into their weekly routine report higher levels of creativity, more energy, increased focus, and improved relational skills, as well as reduced anxiety, stress, and even depression. To learn more about micro dosing check out our Ultimate Guide to Micro dosing Psilocybin Mushrooms. Growing your own mushrooms gives you the independence to gain ownership of your mental wellbeing we’ve got you covered from start to finish.

Need a more hands-on and guided approach? Our friends at Double Blind Mag teach you how to grow your own mushrooms with experienced mycology experts and support along every step of the way with their How To Grow Your Own Mushrooms course. Click here to get started.

Molly MDMA

INTRODUCTION TO MOLLY(MDMA/ECSTASY)

Molly 3,4-methylenedioxy-methamphetamine (MDMA) is a synthetic drug that alters mood and perception (awareness of surrounding objects and conditions). Molly is chemically similar to both stimulants and hallucinogens, producing feelings of increased energy, pleasure, emotional warmth, and distorted sensory and time perception.

Molly MDMA was initially popular in the nightclub scene and at all-night dance parties (“raves”), but the drug now affects a broader range of people who more commonly call the drug Ecstasy or Molly.

How do people use Molly MDMA?

People who use MDMA usually take it as a capsule or tablet, though some swallow it in liquid form or snort the powder. The popular nickname Molly (slang for “molecular”) often refers to the supposedly “pure” crystalline powder form of MDMA, usually sold in capsules. However, people who purchase powder or capsules sold as Molly often actually get other drugs such as synthetic cathinones (“bath salts”) instead (see “Added Risk of MDMA”).

Some people take Molly MDMA in combination with other drugs such as alcohol or marijuana.

How does Molly MDMA affect the brain?

Molly MDMA increases the activity of three brain chemicals:

  • Dopamine—produces increased energy/activity and acts in the reward system to reinforce behaviors
  • Norepinephrine—increases heart rate and blood pressure, which are particularly risky for people with heart and blood vessel problems
  • Serotonin—affects mood, appetite, sleep, and other functions. It also triggers hormones that affect sexual arousal and trust. The release of large amounts of serotonin likely causes the emotional closeness, elevated mood, and empathy felt by those who use MDMA.

Other health effects include:

  • nausea
  • muscle cramping
  • involuntary teeth clenching
  • blurred vision
  • chills
  • sweating

Molly MDMA’s effects last about 3 to 6 hours, although many users take a second dose as the effects of the first dose begin to fade. Over the course of the week following moderate use of the drug, a person may experience:

  • irritability
  • impulsiveness and aggression
  • depression
  • sleep problems
  • anxiety
  • memory and attention problems
  • decreased appetite
  • decreased interest in and pleasure from sex

It’s possible that some of these effects may be due to the combined use of MDMA with other drugs, especially marijuana.

What are other health effects of Molly MDMA?

High doses of Molly MDMA can affect the body’s ability to regulate temperature. This can lead to a spike in body temperature that can occasionally result in liver, kidney, or heart failure or even death.

In addition, because MDMA can promote trust and closeness, its use—especially combined with sildenafil (Viagra®)—may encourage unsafe sexual behavior. This increases people’s risk of contracting or transmitting HIV/AIDS or hepatitis.

Read more about drug use and HIV/AIDS in DrugFacts: HIV/AIDS and Drug Abuse

Read more about drug use and hepatitis.

Added Risk of Molly MDMA

Adding to MDMA’s risks is that pills, capsules, or powders sold as Ecstasy and supposedly “pure” Molly may contain other drugs instead of or in addition to MDMA. Much of the Molly seized by the police contains additives such as cocaine, ketamine, methamphetamine, over-the-counter cough medicine, or synthetic cathinones (“bath salts”). These substances may be extremely dangerous if the person does not know what he or she is taking. They may also be dangerous when combined with MDMA. People who purposely or unknowingly combine such a mixture with other substances, such as marijuana and alcohol, may be putting themselves at even higher risk for harmful health effects.

Is Molly MDMA addictive?

Research results vary on whether MDMA is addictive. Experiments have shown that animals will self-administer MDMA—an important indicator of a drug’s abuse potential—although to a lesser degree than some other drugs such as cocaine.

Some people report signs of addiction, including the following withdrawal symptoms:

  • fatigue
  • loss of appetite
  • depression
  • trouble concentrating

Does MDMA Have Value in Therapy?

Molly MDMA was first used in the 1970s as an aid in psychotherapy (mental disorder treatment using “talk therapy”). The drug did not have the support of clinical trials (studies using humans) or approval from the U.S. Food and Drug Administration (FDA). In 1985, The U.S. Drug Enforcement Administration (DEA) labeled Molly MDMA as an illegal drug with no recognized medicinal use. However, some researchers remain interested in its value in psychotherapy when given to patients under carefully controlled conditions. MDMA is currently in clinical trials as a possible treatment aid for post-traumatic stress disorder (PTSD); for anxiety in terminally ill patients; and for social anxiety in autistic adults. Recently, the FDA gave MDMA-assisted psychotherapy for PTSD a Breakthrough Therapy designation. More information on MDMA research can be found by contacting sponsors of various MDMA studies listed on clinicaltrials.gov.

How can people get treatment for addiction to MDMA?

There are no specific medical treatments for MDMA addiction. Some people seeking treatment for MDMA addiction have found behavioral therapy to be helpful. Scientists need more research to determine how effective this treatment option is for addiction to MDMA.

Points to Remember

  • 3,4-methylenedioxy-methamphetamine (MDMA) is a synthetic drug that alters mood and perception. It is chemically similar to stimulants and hallucinogens.
  • MDMA is commonly called Ecstasy or Molly.
  • People who use MDMA typically take it as a capsule or tablet. Many people take it in combination with other drugs.
  • MDMA acts by increasing the activity of three brain chemicals: dopamine, norepinephrine, and serotonin.
  • Effects include increased energy, distorted perception, involuntary teeth clenching, dangerously high body temperature, and depression.
  • Many people are unaware that Ecstasy and supposedly “pure” Molly also often contain not only pure MDMA but other drugs that may be particularly dangerous when mixed with MDMA.
  • Research results vary on whether MDMA is addictive. Some people report signs of addiction.
  • Some people seeking treatment for MDMA addiction have found behavioral therapy to be helpful. There are no specific medical treatments for MDMA addiction.